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Sindromi radiologiche del torace

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Clinical and radiological manifestations of pancreatic toxicity during systemic ChT and abdominal RT range from asymptomatic increase in blood pancreatic enzymes levels, to acute pancreatitis (AP) or parenchymal atrophy with exocrine insufficiency. In addition, ChT/RT for pancreatic ductal adenocarcinoma (PDAC) may induce changes in peri-pancreatic tissues, particularly at the interface between tumor mass and peri-pancreatic vessels. While asymptomatic increase in serum levels of pancreatic enzymes have been found in up to 30–56% of patients treated with sunitinib and sorafenib, ChT-related AP seems to be much less frequent, although its true incidence is unknown, as the causal relationship between the drug and AP may be difficult to determine [ 57]. Several drugs can induce AP: all-trans retinoic acids, cytarabine, and L-asparaginase used to treat leukemia, vascular endothelial growth factor receptor (VEGFR) and tyrosine kinase inhibitors, ICIs and drugs like gemcitabine and capecitabine, which are commonly used in PDAC treatment [ 10, 57]. It has been postulated that capecitabine- and pazopanib-induced hypertriglyceridemia may lead to AP [ 57]; other factors that can contribute to AP can be a direct toxic effect, an allergic reaction or immune-related events. In general, imaging findings of ChT-associated AP do not differ from their non-drug-induced counterparts: enlargement of the pancreas, decreased parenchymal enhancement, peripancreatic fat stranding, fluid collections, and, in severe forms, intra- and peri-pancreatic necrosis. Chronic inflammatory demyelinating polyneuropathy (CIDP) is considered the chronic counterpart to Guillain-Barré syndrome. Radiographic features Diagnosi della displasia dell'anca · Studio del fegato · Studio del sistema linfatico · studio del sistema osteo-articolare · Studio della patologia articolare e dei tessuti molli · Studio della patologia non oncologica dello scheletro · Studio della patologia oncologica dello scheletro · Studio radiografico dell'apparato digerente superiore

Mittal S, Singh A, Gold M, Leung A, Haramati L, Katz D. Thoracic Imaging Features of Legionnaire's Disease. Infect Dis Clin North Am. 2017;31(1):43-54. doi:10.1016/j.idc.2016.10.004 - Pubmed

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Angiotermografia dinamica · Cateterismo cardiaco · Chemioembolizzazione · Clisma opaco · Colangio-pancreatografia endoscopica retrograda · Coronarografia · Embolizzazione · Embolizzazione dell'arteria epatica · Filtro cavale · Iodocaptazione · Radioembolizzazione intrarteriosa delle neoplasie primitive e delle metastasi epatiche · Shunt portosistemico intraepatico transgiugulare · Spirale endovascolare · Ventricolografia cardiaca · Vertebroplastica percutanea

Another limitation that reduces the generalizability of these observations is represented by the multiple kinds of image modalities and, for each of them, the variability of acquisition protocols. Moreover, the huge heterogeneity of features analyzed in the different studies poses a limitation in the possibility of creating a cluster of significant features for radiomics in this pathology. The same number of features analyzed, study by study, is very variable (from 1 to 3328 features per study) documenting that the resulting models are very much linked to the analysis experience of each centre. Franquet T, Müller N, Giménez A, Guembe P, de la Torre J, Bagué S. Spectrum of Pulmonary Aspergillosis: Histologic, Clinical, and Radiologic Findings. Radiographics. 2001;21(4):825-37. doi:10.1148/radiographics.21.4.g01jl03825Tan M, Tan J, Hamor R, File T, Breiman R. The Radiologic Manifestations of Legionnaire's Disease. The Ohio Community-Based Pneumonia Incidence Study Group. Chest. 2000;117(2):398-403. doi:10.1378/chest.117.2.398 - Pubmed Division of Pulmonary and Critical Care Medicine, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea. Godet C, Frat JP, Le Moal G et-al. Legionnaire's pneumonia: is there really an interstitial disease?. Eur J Radiol. 2007;61 (1): 150-3. doi:10.1016/j.ejrad.2006.08.020 - Pubmed citation Daily practice and research in oncology are shifting toward precision medicine, with treatments targeted to specific patient and tumor profiles [ 1, 2]. This underlying concept of health care enables to personalize chemotherapy (ChT) and radiotherapy (RT) schemes improving safety and effectiveness [ 3]. Meanwhile, advancements in oncology imaging walk hand-in-hand with new treatment strategies. Fast and highly performing CT and MRI technologies have opened new frontiers in oncology imaging, allowing tissue characterization, early diagnosis, prognostic evaluation, and accurate response assessment; this innovative approach results in shifting the radiological assessment from the mere morphologic evaluation to obtaining qualitative and functional data that can be combined with patients clinical information [ 4– 7]. Funding: The authors received no financial support for the research, authorship, and/or publication of this article.

The combination of CT delta radiomics and the clinical biomarker CA19-9 leads to improved prediction of treatment responses for chemoRT of PC, as compared with radiomics or CA19-9 alone. The prediction model identifies PDAC from autoimmune pancreatitis with a sensitivity, specificity and accuracy of 93.3%, 96.1% and 94.8%, respectively. Section of Scienze Radiologiche, Department of Medicine and Surgery (DiMeC), University of Parma, Parma, Italy. Guillain-Barré syndrome is primarily managed with IV immunoglobulin or plasmapheresis along with supportive measures, which can speed up recovery 1. Typically improvement occurs after a number of weeks to months 1 although there is significant mortality (3-10%) 5. History and etymologyTo predict distant relapse FS in patients with locally advanced PDAC who underwent radiochemotherapy Within this heterogeneous group of papers, four articles 62, 66, 72, 74 analyzed the role of CT-based radiomics in lymph nodes (LNs) metastasis risk assessment before surgery. The preoperative evaluation of the risk of a positive resection margin using CT-based radiomics analysis was the aim of three papers. 58, 69, 76 Zhang et al. 61 evaluated the risk of occurrence of pancreatic fistula using a CT-based radiomic model. Overall, 13 articles 40, 47, 48, 63 – 65, 68, 70, 71, 73, 75, 77, 78 analyzed the role of radiomics to predict clinical outcomes, such as OS, progression-free survival (PFS) and early relapse. Mathas S, Hartmann S, Küppers R. Hodgkin lymphoma: pathology and biology. Semin Hematol. 2016;53:139‐147. The quantitative analysis of medical images data and the extraction of imaging features, also called ‘radiomics’, represent an emerging approach in personalized medicine and advanced diagnostics, especially for disease characterization or outcome prediction. 11 – 13 The interest towards radiomics is rapidly growing in the multidisciplinary cancer community as it shows an interesting pertinency and efficacy to answer several clinical questions arising in the management of patients affected by other gastrointestinal tumours. 14 – 21

Locoregional metabolic texture response provides a feasible approach for evaluating and predicting clinical outcomes following the treatment of pancreatic adenocarcinoma with RT. Haroon A, Higa F, Hibiya K et-al. Organizing pneumonia pattern in the follow-up CT of Legionella-infected patients. J. Infect. Chemother. 2011;17 (4): 493-8. doi:10.1007/s10156-010-0205-y - Pubmed citation The model obtained an AUC of 0.769 and of 0.729 in the training and in the validation cohort, respectively. Angiografia ( con fluorescina) · Mineralometria ossea computerizzata · Neuroimaging · Tomografia computerizzata cardiaca · Tomografia computerizzata cone beam · Radiologia domiciliare · Termografia mammaria · Tomografia ( a fascio di elettroni · computerizzata (TAC)) Deeg JH, Bredeson C, Farnia S, et al. Hematopoietic cell transplantation as curative therapy for patients with myelofibrosis: long-term success in all age groups. Biol Blood Marrow Transplant. 2015;21(11):1883-1887.To identify imaging characteristics in patients with known pNET that predict the ALT phenotype by blinded retrospective review of preoperative multiphasic CT scans

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